EPO anticorps

N° du produit ABIN7670596

Cet anticorps anti-EPO est un anticorps Rat Monoclonal détectant EPO dans ELISA (Capture). Adapté pour Souris.

Aperçu rapide pour EPO anticorps (ABIN7670596)

Antigène: EPO (Erythropoietin (EPO))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp EPO est non-conjugé

Application: ELISA (Capture)

Clone: 8C3

Détail du produit anti-EPO anticorps

Fonction: Erythropoietin/EPO Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogène: Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli

Isotype: IgG2a

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur EPO

Antigène: EPO (Erythropoietin (EPO))

Autre désignation: Erythropoietin/EPO

Classe de substances: Hormone

Sujet: MGC,ECYT,MVCD,Hematopoietin,Hemopoietin,ECYT5,EP,epoetin,Erythropoietin,MGC138142,MVCD2,Epo,This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

UniProt: P07321

Pathways: Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity